Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mrdAPenicillin-binding protein 2 (PBP-2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (627 aa)    
Predicted Functional Partners:
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 0.999
EEX38356.1
Multimodular transpeptidase-transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
 
 0.989
ftsW
Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
 0.977
EEX38133.1
Multimodular transpeptidase-transglycosylase.
 
 
 0.974
EEX37616.1
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
 
 0.970
EEX37982.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.967
ftsI
Cell division protein FtsI [Peptidoglycan synthetase]; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
  
  
0.962
EEX37983.1
Rod shape-determining protein MreB.
 
 
 
 0.933
EEX36089.1
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
 
 0.923
ftsQ
Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
  
 
 0.907
Your Current Organism:
Vibrio metschnikovii
NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14
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