| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX36350.1 | EEX37634.1 | VIB_002665 | VIB_001759 | Inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family. | Decarboxylase family protein. | 0.802 |
| EEX36350.1 | tadA | VIB_002665 | VIB_001785 | Inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family. | tRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.697 |
| EEX36350.1 | upp | VIB_002665 | VIB_000699 | Inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.895 |
| EEX37634.1 | EEX36350.1 | VIB_001759 | VIB_002665 | Decarboxylase family protein. | Inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family. | 0.802 |
| EEX37634.1 | tadA | VIB_001759 | VIB_001785 | Decarboxylase family protein. | tRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.693 |
| EEX37634.1 | upp | VIB_001759 | VIB_000699 | Decarboxylase family protein. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.868 |
| EEX37661.1 | EEX37662.1 | VIB_001786 | VIB_001787 | Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.727 |
| EEX37661.1 | tadA | VIB_001786 | VIB_001785 | Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | tRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.689 |
| EEX37662.1 | EEX37661.1 | VIB_001787 | VIB_001786 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | 0.727 |
| EEX37662.1 | tadA | VIB_001787 | VIB_001785 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | tRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.902 |
| EEX38341.1 | birA | VIB_000286 | VIB_003105 | Glycerate kinase; Belongs to the glycerate kinase type-1 family. | Biotin-protein ligase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.613 |
| EEX38341.1 | tadA | VIB_000286 | VIB_001785 | Glycerate kinase; Belongs to the glycerate kinase type-1 family. | tRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.684 |
| birA | EEX38341.1 | VIB_003105 | VIB_000286 | Biotin-protein ligase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Glycerate kinase; Belongs to the glycerate kinase type-1 family. | 0.613 |
| birA | guaA | VIB_003105 | VIB_001846 | Biotin-protein ligase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.684 |
| birA | ribB | VIB_003105 | VIB_000657 | Biotin-protein ligase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.633 |
| birA | tadA | VIB_003105 | VIB_001785 | Biotin-protein ligase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | tRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.919 |
| guaA | birA | VIB_001846 | VIB_003105 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Biotin-protein ligase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.684 |
| guaA | hisI | VIB_001846 | VIB_001086 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.486 |
| guaA | ribB | VIB_001846 | VIB_000657 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.721 |
| guaA | tadA | VIB_001846 | VIB_001785 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | tRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.716 |