| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX37742.1 | EEX37817.1 | VIB_001868 | VIB_001945 | Putative acetoin utilization protein AcuB. | Glutamate synthase [NADPH] large chain. | 0.421 |
| EEX37742.1 | EEX37948.1 | VIB_001868 | VIB_002080 | Putative acetoin utilization protein AcuB. | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.408 |
| EEX37742.1 | EEX38006.1 | VIB_001868 | VIB_002140 | Putative acetoin utilization protein AcuB. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.630 |
| EEX37742.1 | gpt | VIB_001868 | VIB_000649 | Putative acetoin utilization protein AcuB. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.446 |
| EEX37742.1 | guaA | VIB_001868 | VIB_001846 | Putative acetoin utilization protein AcuB. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.851 |
| EEX37742.1 | queA | VIB_001868 | VIB_001867 | Putative acetoin utilization protein AcuB. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.672 |
| EEX37742.1 | secD | VIB_001868 | VIB_001864 | Putative acetoin utilization protein AcuB. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.576 |
| EEX37742.1 | secF | VIB_001868 | VIB_001863 | Putative acetoin utilization protein AcuB. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.537 |
| EEX37742.1 | tgt | VIB_001868 | VIB_001866 | Putative acetoin utilization protein AcuB. | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | 0.642 |
| EEX37742.1 | yajC | VIB_001868 | VIB_001865 | Putative acetoin utilization protein AcuB. | Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.600 |
| EEX37817.1 | EEX37742.1 | VIB_001945 | VIB_001868 | Glutamate synthase [NADPH] large chain. | Putative acetoin utilization protein AcuB. | 0.421 |
| EEX37817.1 | EEX37948.1 | VIB_001945 | VIB_002080 | Glutamate synthase [NADPH] large chain. | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.510 |
| EEX37817.1 | EEX38006.1 | VIB_001945 | VIB_002140 | Glutamate synthase [NADPH] large chain. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.575 |
| EEX37817.1 | gpt | VIB_001945 | VIB_000649 | Glutamate synthase [NADPH] large chain. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.401 |
| EEX37817.1 | guaA | VIB_001945 | VIB_001846 | Glutamate synthase [NADPH] large chain. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.959 |
| EEX37817.1 | secD | VIB_001945 | VIB_001864 | Glutamate synthase [NADPH] large chain. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.835 |
| EEX37948.1 | EEX37742.1 | VIB_002080 | VIB_001868 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative acetoin utilization protein AcuB. | 0.408 |
| EEX37948.1 | EEX37817.1 | VIB_002080 | VIB_001945 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate synthase [NADPH] large chain. | 0.510 |
| EEX37948.1 | gpt | VIB_002080 | VIB_000649 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.896 |
| EEX37948.1 | guaA | VIB_002080 | VIB_001846 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.943 |