nfo protein (Vibrio metschnikovii) - STRING interaction network

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nfo

Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (294 aa)

Predicted Functional Partners:

ung

0.950

EEX36850.1

0.907

nth

0.852

hisB

0.757

EEX37325.1

0.713

EEX37626.1

0.685

polA

0.682

EEX37805.1

0.666

grcA

0.658

lolB

0.576

Your Current Organism:

Vibrio metschnikovii

NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEX36850.1	EEX37325.1	VIB_000957	VIB_001445	Exodeoxyribonuclease III.	DNA polymerase II.	0.527
EEX36850.1	EEX37626.1	VIB_000957	VIB_001751	Exodeoxyribonuclease III.	D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase.	0.705
EEX36850.1	hisB	VIB_000957	VIB_001082	Exodeoxyribonuclease III.	Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; In the N-terminal section; belongs to the histidinol- phosphatase family.	0.750
EEX36850.1	nfo	VIB_000957	VIB_001935	Exodeoxyribonuclease III.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.907
EEX36850.1	nth	VIB_000957	VIB_001689	Exodeoxyribonuclease III.	Predicted EndoIII-related endonuclease; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.926
EEX36850.1	polA	VIB_000957	VIB_000051	Exodeoxyribonuclease III.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.793
EEX36850.1	ung	VIB_000957	VIB_001934	Exodeoxyribonuclease III.	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.799
EEX37325.1	EEX36850.1	VIB_001445	VIB_000957	DNA polymerase II.	Exodeoxyribonuclease III.	0.527
EEX37325.1	nfo	VIB_001445	VIB_001935	DNA polymerase II.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.713
EEX37325.1	nth	VIB_001445	VIB_001689	DNA polymerase II.	Predicted EndoIII-related endonuclease; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.485
EEX37325.1	polA	VIB_001445	VIB_000051	DNA polymerase II.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.917
EEX37626.1	EEX36850.1	VIB_001751	VIB_000957	D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase.	Exodeoxyribonuclease III.	0.705
EEX37626.1	nfo	VIB_001751	VIB_001935	D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.685
EEX37805.1	grcA	VIB_001933	VIB_001936	Hypothetical protein.	Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.	0.486
EEX37805.1	nfo	VIB_001933	VIB_001935	Hypothetical protein.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.666
EEX37805.1	ung	VIB_001933	VIB_001934	Hypothetical protein.	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.730
grcA	EEX37805.1	VIB_001936	VIB_001933	Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.	Hypothetical protein.	0.486
grcA	nfo	VIB_001936	VIB_001935	Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.658
grcA	ung	VIB_001936	VIB_001934	Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.581
hisB	EEX36850.1	VIB_001082	VIB_000957	Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; In the N-terminal section; belongs to the histidinol- phosphatase family.	Exodeoxyribonuclease III.	0.750

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