| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX36068.1 | EEX37643.1 | VIB_002382 | VIB_001768 | hydroxymethylglutaryl-CoA reductase. | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 0.577 |
| EEX36068.1 | EEX37968.1 | VIB_002382 | VIB_002100 | hydroxymethylglutaryl-CoA reductase. | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 0.650 |
| EEX36068.1 | menA | VIB_002382 | VIB_000473 | hydroxymethylglutaryl-CoA reductase. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.758 |
| EEX36589.1 | EEX37643.1 | VIB_000690 | VIB_001768 | SAM-dependent methyltransferase. | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 0.661 |
| EEX36589.1 | EEX37968.1 | VIB_000690 | VIB_002100 | SAM-dependent methyltransferase. | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 0.661 |
| EEX36759.1 | EEX37643.1 | VIB_000865 | VIB_001768 | rRNA (guanine-N1-)-methyltransferase. | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 0.661 |
| EEX36759.1 | EEX37968.1 | VIB_000865 | VIB_002100 | rRNA (guanine-N1-)-methyltransferase. | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 0.661 |
| EEX37643.1 | EEX36068.1 | VIB_001768 | VIB_002382 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | hydroxymethylglutaryl-CoA reductase. | 0.577 |
| EEX37643.1 | EEX36589.1 | VIB_001768 | VIB_000690 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | SAM-dependent methyltransferase. | 0.661 |
| EEX37643.1 | EEX36759.1 | VIB_001768 | VIB_000865 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | rRNA (guanine-N1-)-methyltransferase. | 0.661 |
| EEX37643.1 | EEX37968.1 | VIB_001768 | VIB_002100 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 0.943 |
| EEX37643.1 | bioC | VIB_001768 | VIB_001494 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | Biotin synthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.676 |
| EEX37643.1 | menA | VIB_001768 | VIB_000473 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.468 |
| EEX37643.1 | trpC | VIB_001768 | VIB_001485 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | Indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Belongs to the TrpC family. | 0.665 |
| EEX37643.1 | ubiA | VIB_001768 | VIB_000089 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.702 |
| EEX37643.1 | ubiE | VIB_001768 | VIB_000043 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.676 |
| EEX37643.1 | uppS | VIB_001768 | VIB_000669 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.974 |
| EEX37968.1 | EEX36068.1 | VIB_002100 | VIB_002382 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | hydroxymethylglutaryl-CoA reductase. | 0.650 |
| EEX37968.1 | EEX36589.1 | VIB_002100 | VIB_000690 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | SAM-dependent methyltransferase. | 0.661 |
| EEX37968.1 | EEX36759.1 | VIB_002100 | VIB_000865 | Octaprenyl-diphosphate synthase/dimethylallyltransferase/geranyltranstransferase/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | rRNA (guanine-N1-)-methyltransferase. | 0.661 |