| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX36020.1 | EEX37948.1 | VIB_002333 | VIB_002080 | Inosine-guanosine kinase. | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.870 |
| EEX36020.1 | EEX38066.1 | VIB_002333 | VIB_000436 | Inosine-guanosine kinase. | Guanylate kinase. | 0.870 |
| EEX36020.1 | EEX38367.1 | VIB_002333 | VIB_000313 | Inosine-guanosine kinase. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.870 |
| EEX36020.1 | EEX38402.1 | VIB_002333 | VIB_000348 | Inosine-guanosine kinase. | MazG protein. | 0.873 |
| EEX36020.1 | add | VIB_002333 | VIB_000391 | Inosine-guanosine kinase. | Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.956 |
| EEX36020.1 | gpt | VIB_002333 | VIB_000649 | Inosine-guanosine kinase. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.920 |
| EEX36020.1 | guaA | VIB_002333 | VIB_001846 | Inosine-guanosine kinase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.884 |
| EEX36020.1 | purA | VIB_002333 | VIB_000533 | Inosine-guanosine kinase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.919 |
| EEX36020.1 | purA-2 | VIB_002333 | VIB_002599 | Inosine-guanosine kinase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.919 |
| EEX36020.1 | purH | VIB_002333 | VIB_002873 | Inosine-guanosine kinase. | IMP cyclohydrolase/phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.880 |
| EEX37948.1 | EEX36020.1 | VIB_002080 | VIB_002333 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine-guanosine kinase. | 0.870 |
| EEX37948.1 | EEX38367.1 | VIB_002080 | VIB_000313 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.871 |
| EEX37948.1 | add | VIB_002080 | VIB_000391 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.426 |
| EEX37948.1 | gpt | VIB_002080 | VIB_000649 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.896 |
| EEX37948.1 | guaA | VIB_002080 | VIB_001846 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.943 |
| EEX37948.1 | purA | VIB_002080 | VIB_000533 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.920 |
| EEX37948.1 | purA-2 | VIB_002080 | VIB_002599 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.923 |
| EEX37948.1 | purH | VIB_002080 | VIB_002873 | Nucleoside 5-triphosphatase RdgB (dHAPTP dITP XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | IMP cyclohydrolase/phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.885 |
| EEX38066.1 | EEX36020.1 | VIB_000436 | VIB_002333 | Guanylate kinase. | Inosine-guanosine kinase. | 0.870 |
| EEX38066.1 | EEX38367.1 | VIB_000436 | VIB_000313 | Guanylate kinase. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.914 |
