| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX36023.1 | EEX37817.1 | VIB_002336 | VIB_001945 | Aminomethyltransferase (glycine cleavage system T protein). | Glutamate synthase [NADPH] large chain. | 0.890 |
| EEX36023.1 | EEX38370.1 | VIB_002336 | VIB_000316 | Aminomethyltransferase (glycine cleavage system T protein). | Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. | 0.846 |
| EEX36023.1 | EEX38371.1 | VIB_002336 | VIB_000317 | Aminomethyltransferase (glycine cleavage system T protein). | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.661 |
| EEX36023.1 | gcvH | VIB_002336 | VIB_002338 | Aminomethyltransferase (glycine cleavage system T protein). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| EEX36023.1 | gcvP | VIB_002336 | VIB_002339 | Aminomethyltransferase (glycine cleavage system T protein). | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
| EEX36023.1 | glyA | VIB_002336 | VIB_001745 | Aminomethyltransferase (glycine cleavage system T protein). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.995 |
| EEX36023.1 | purD | VIB_002336 | VIB_002874 | Aminomethyltransferase (glycine cleavage system T protein). | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.768 |
| EEX36023.1 | purL | VIB_002336 | VIB_001782 | Aminomethyltransferase (glycine cleavage system T protein). | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.771 |
| EEX37238.1 | EEX37239.1 | VIB_001354 | VIB_001355 | Fumarate hydratase class I aerobic. | Fumarate hydratase class I. | 0.999 |
| EEX37238.1 | gcvP | VIB_001354 | VIB_002339 | Fumarate hydratase class I aerobic. | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.990 |
| EEX37238.1 | glyA | VIB_001354 | VIB_001745 | Fumarate hydratase class I aerobic. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.446 |
| EEX37239.1 | EEX37238.1 | VIB_001355 | VIB_001354 | Fumarate hydratase class I. | Fumarate hydratase class I aerobic. | 0.999 |
| EEX37239.1 | gcvP | VIB_001355 | VIB_002339 | Fumarate hydratase class I. | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.990 |
| EEX37239.1 | glyA | VIB_001355 | VIB_001745 | Fumarate hydratase class I. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.446 |
| EEX37817.1 | EEX36023.1 | VIB_001945 | VIB_002336 | Glutamate synthase [NADPH] large chain. | Aminomethyltransferase (glycine cleavage system T protein). | 0.890 |
| EEX37817.1 | EEX38370.1 | VIB_001945 | VIB_000316 | Glutamate synthase [NADPH] large chain. | Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. | 0.862 |
| EEX37817.1 | EEX38371.1 | VIB_001945 | VIB_000317 | Glutamate synthase [NADPH] large chain. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.863 |
| EEX37817.1 | gcvH | VIB_001945 | VIB_002338 | Glutamate synthase [NADPH] large chain. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.866 |
| EEX37817.1 | gcvP | VIB_001945 | VIB_002339 | Glutamate synthase [NADPH] large chain. | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.945 |
| EEX37817.1 | glyA | VIB_001945 | VIB_001745 | Glutamate synthase [NADPH] large chain. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.879 |