Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EEX36127.1Transcriptional regulator GntR family. (475 aa)    
Predicted Functional Partners:
EEX37817.1
Glutamate synthase [NADPH] large chain.
   
 
  0.844
EEX37459.1
Aspartate/tyrosine/aromatic aminotransferase.
  
 0.837
EEX38004.1
Serine--pyruvate aminotransferase/L-alanine:glyoxylate aminotransferase.
  
 
 0.829
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.828
gcvP
Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.823
EEX38028.1
Glutamine synthetase type I.
    
 0.820
EEX38247.1
Hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
  0.819
EEX36023.1
Aminomethyltransferase (glycine cleavage system T protein).
  
 
  0.818
EEX38370.1
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex.
     
  0.813
EEX37521.1
Alanine dehydrogenase; Belongs to the AlaDH/PNT family.
     
  0.813
Your Current Organism:
Vibrio metschnikovii
NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14
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