Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nnrEYjeF protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of [...] (491 aa)    
Predicted Functional Partners:
EEX38047.1
ADP compounds hydrolase NudE; Belongs to the Nudix hydrolase family.
 
 0.824
EEX36003.1
ADP-ribose pyrophosphatase.
 
 0.821
EEX38390.1
ADP-ribose pyrophosphatase.
  
 0.795
EEX37829.1
MutT protein [7,8-dihydro-8-oxoguanine-triphosphatase]; Belongs to the Nudix hydrolase family.
  
 0.795
groL
Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.760
EEX36753.1
Pyruvate-flavodoxin oxidoreductase.
  
   0.743
srmB
ATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily.
   
  0.717
EEX38196.1
ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family.
   
  0.717
EEX37668.1
ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.
   
  0.717
EEX36005.1
ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.
   
  0.717
Your Current Organism:
Vibrio metschnikovii
NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14
Server load: medium (42%) [HD]