STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
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Coexpression
Experiments
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[Homology]
Score
EEX36338.1Isochorismate synthase of siderophore biosynthesis. (393 aa)    
Predicted Functional Partners:
EEX36336.1
Isochorismatase of siderophore biosynthesis.
 
 
 0.999
EEX36337.1
2,3-dihydroxybenzoate-AMP ligase.
 
 
 0.997
EEX36330.1
Non-ribosomal peptide synthetase modules and related protein.
 
 
 0.987
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 0.986
EEX37363.1
Anthranilate synthase amidotransferase component.
  
  
 0.961
EEX36339.1
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase.
 
  
 0.948
EEX38265.1
Chorismate mutase I/cyclohexadienyl dehydrogenase.
  
 
 0.926
EEX38259.1
Chorismate mutase I/prephenate dehydratase.
  
 
 0.925
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.907
EEX37362.1
Anthranilate synthase aminase component.
  
  
0.906
Your Current Organism:
Vibrio metschnikovii
NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14
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