STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEX35845.1HTH-type transcriptional regulator IlvY; Belongs to the LysR transcriptional regulatory family. (295 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
     0.748
EEX35712.1
Regulatory protein CysB; Belongs to the LysR transcriptional regulatory family.
  
     0.681
EEX36442.1
Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.627
EEX37115.1
Transcriptional regulator LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.596
EEX37292.1
Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.540
EEX36395.1
Transcriptional regulator LysR family; Predicted Lactate-responsive regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.536
EEX37464.1
Transcriptional regulator LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.477
Your Current Organism:
Vibrio metschnikovii
NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14
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