| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEX35648.1 | EEX36981.1 | VIB_003017 | VIB_001090 | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | 0.916 |
| EEX35648.1 | EEX38028.1 | VIB_003017 | VIB_000397 | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | Glutamine synthetase type I. | 0.776 |
| EEX35648.1 | clpB | VIB_003017 | VIB_000199 | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.916 |
| EEX35648.1 | dnaJ | VIB_003017 | VIB_001794 | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.711 |
| EEX35648.1 | dnaK | VIB_003017 | VIB_001795 | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.727 |
| EEX35648.1 | grpE | VIB_003017 | VIB_001796 | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.786 |
| EEX35648.1 | hslU | VIB_003017 | VIB_000472 | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent hsl protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.701 |
| EEX35648.1 | hslV | VIB_003017 | VIB_000471 | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.728 |
| EEX35648.1 | htpG | VIB_003017 | VIB_001710 | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.724 |
| EEX35648.1 | malT | VIB_003017 | VIB_002537 | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | Transcriptional activator of maltose regulon MalT; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box. | 0.716 |
| EEX36981.1 | EEX35648.1 | VIB_001090 | VIB_003017 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | 0.916 |
| EEX36981.1 | dnaJ | VIB_001090 | VIB_001794 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.854 |
| EEX36981.1 | dnaK | VIB_001090 | VIB_001795 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.896 |
| EEX36981.1 | grpE | VIB_001090 | VIB_001796 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.857 |
| EEX36981.1 | hslU | VIB_001090 | VIB_000472 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent hsl protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.705 |
| EEX36981.1 | hslV | VIB_001090 | VIB_000471 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.583 |
| EEX36981.1 | htpG | VIB_001090 | VIB_001710 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.863 |
| EEX38028.1 | EEX35648.1 | VIB_000397 | VIB_003017 | Glutamine synthetase type I. | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | 0.776 |
| EEX38028.1 | dnaJ | VIB_000397 | VIB_001794 | Glutamine synthetase type I. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.403 |
| clpB | EEX35648.1 | VIB_000199 | VIB_003017 | ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Heat shock protein A; Belongs to the small heat shock protein (HSP20) family. | 0.916 |
