STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hflXGTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (429 aa)    
Predicted Functional Partners:
rplI
LSU ribosomal protein L9p; Binds to the 23S rRNA.
 
 
 
 0.936
EEX35596.1
HflK protein; HflC and HflK could encode or regulate a protease.
  
  
 0.922
rplK
LSU ribosomal protein L11p (L12e); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
 
 0.920
rplC
LSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
    
 
 0.918
rplX
LSU ribosomal protein L24p (L26e); One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
  
 
   0.916
rplD
LSU ribosomal protein L4p (L1e); Forms part of the polypeptide exit tunnel.
    
 
 0.913
rpmF
LSU ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family.
    
 
 0.913
rplR
LSU ribosomal protein L18p (L5e); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
 
   0.912
rplM
LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
 
 0.912
rplS
LSU ribosomal protein L19p; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
   0.911
Your Current Organism:
Vibrio metschnikovii
NCBI taxonomy Id: 675813
Other names: V. metschnikovii CIP 69.14, Vibrio metschnikovii CIP 69.14, Vibrio metschnikovii str. CIP 69.14, Vibrio metschnikovii strain CIP 69.14
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