STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflAPyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (215 aa)    
Predicted Functional Partners:
EEX92678.1
Pyruvate formate-lyase.
 
  
 0.950
EEX92868.1
Alcohol dehydrogenase; Most likely function alternative not yet resolved; acetaldehyde dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.848
grcA
Pyruvate formate-lyase; Acts as a radical domain for damaged PFL and possibly other radical proteins.
  
     0.774
EEX92682.1
Hypothetical protein; Belongs to the UPF0304 family.
       0.502
EEX92717.1
Phosphate acetyltransferase.
     
 0.487
EEX92680.1
Methyl-accepting chemotaxis protein.
       0.457
EEX93579.1
Alcohol dehydrogenase iron-containing.
  
  
 0.445
EEX93721.1
Alcohol dehydrogenase.
  
  
 0.445
EEX93786.1
Alcohol dehydrogenase.
  
  
 0.445
EEX92669.1
Iron-containing alcohol dehydrogenase.
  
  
 0.445
Your Current Organism:
Vibrio orientalis
NCBI taxonomy Id: 675816
Other names: V. orientalis CIP 102891 = ATCC 33934, Vibrio orientalis ATCC 33934, Vibrio orientalis ATCC 33934 = CIP 102891, Vibrio orientalis CIP 102891, Vibrio orientalis CIP 102891 = ATCC 33934, Vibrio orientalis IFO 15638, Vibrio orientalis LMG 7987
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.