node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEX92784.1 | EEX92806.1 | VIA_003429 | VIA_003451 | DNA polymerase III delta prime subunit. | DinG family ATP-dependent helicase YoaA. | 0.879 |
EEX92784.1 | EEX93135.1 | VIA_003429 | VIA_003782 | DNA polymerase III delta prime subunit. | ATP-dependent DNA helicase RecQ family. | 0.909 |
EEX92784.1 | EEX93845.1 | VIA_003429 | VIA_001003 | DNA polymerase III delta prime subunit. | Exonuclease SbcC. | 0.863 |
EEX92784.1 | EEX95194.1 | VIA_003429 | VIA_000657 | DNA polymerase III delta prime subunit. | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.997 |
EEX92784.1 | EEX95539.1 | VIA_003429 | VIA_000071 | DNA polymerase III delta prime subunit. | ATP-dependent DNA helicase RecQ. | 0.909 |
EEX92784.1 | dinG | VIA_003429 | VIA_002582 | DNA polymerase III delta prime subunit. | ATP-dependent helicase DinG/Rad3; DNA-dependent ATPase and 5'-3' DNA helicase. | 0.894 |
EEX92784.1 | polA | VIA_003429 | VIA_000110 | DNA polymerase III delta prime subunit. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.981 |
EEX92784.1 | recA | VIA_003429 | VIA_003976 | DNA polymerase III delta prime subunit. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.920 |
EEX92784.1 | sbcD | VIA_003429 | VIA_001002 | DNA polymerase III delta prime subunit. | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.921 |
EEX92784.1 | topB | VIA_003429 | VIA_003539 | DNA polymerase III delta prime subunit. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.845 |
EEX92806.1 | EEX92784.1 | VIA_003451 | VIA_003429 | DinG family ATP-dependent helicase YoaA. | DNA polymerase III delta prime subunit. | 0.879 |
EEX92806.1 | EEX93135.1 | VIA_003451 | VIA_003782 | DinG family ATP-dependent helicase YoaA. | ATP-dependent DNA helicase RecQ family. | 0.808 |
EEX92806.1 | EEX93845.1 | VIA_003451 | VIA_001003 | DinG family ATP-dependent helicase YoaA. | Exonuclease SbcC. | 0.832 |
EEX92806.1 | EEX95194.1 | VIA_003451 | VIA_000657 | DinG family ATP-dependent helicase YoaA. | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.875 |
EEX92806.1 | EEX95539.1 | VIA_003451 | VIA_000071 | DinG family ATP-dependent helicase YoaA. | ATP-dependent DNA helicase RecQ. | 0.808 |
EEX92806.1 | polA | VIA_003451 | VIA_000110 | DinG family ATP-dependent helicase YoaA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.984 |
EEX92806.1 | recA | VIA_003451 | VIA_003976 | DinG family ATP-dependent helicase YoaA. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.838 |
EEX92806.1 | sbcD | VIA_003451 | VIA_001002 | DinG family ATP-dependent helicase YoaA. | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.980 |
EEX92806.1 | topB | VIA_003451 | VIA_003539 | DinG family ATP-dependent helicase YoaA. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.820 |
EEX93135.1 | EEX92784.1 | VIA_003782 | VIA_003429 | ATP-dependent DNA helicase RecQ family. | DNA polymerase III delta prime subunit. | 0.909 |