STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crlTranscriptional regulator Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. (95 aa)    
Predicted Functional Partners:
frsA
Hypothetical protein; Belongs to the UPF0255 family.
 
     0.867
rpoS
RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
    
   0.793
EEX95474.1
ATPase of the AAA+ class.
  
     0.769
yieM
Hypothetical protein.
  
     0.768
EEX93292.1
Hypothetical protein.
  
     0.768
zapC
Hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
  
     0.763
EEX91833.1
Protein YciN.
  
     0.760
EEX93403.1
Hypothetical protein.
  
     0.758
zapB
Hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
     0.742
cyaA
Adenylate cyclase.
  
     0.733
Your Current Organism:
Vibrio orientalis
NCBI taxonomy Id: 675816
Other names: V. orientalis CIP 102891 = ATCC 33934, Vibrio orientalis ATCC 33934, Vibrio orientalis ATCC 33934 = CIP 102891, Vibrio orientalis CIP 102891, Vibrio orientalis CIP 102891 = ATCC 33934, Vibrio orientalis IFO 15638, Vibrio orientalis LMG 7987
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.