STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1E3PWS3Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (620 aa)    
Predicted Functional Partners:
A0A1E3QBY3
Uncharacterized protein.
   
 0.997
A0A1E3QAW9
Uncharacterized protein.
    
 0.995
A0A1E3PXP1
DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.
  
 0.989
A0A1E3Q6R8
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.986
A0A1E3PWA3
Uncharacterized protein.
    
 0.985
A0A1E3Q2E8
ERCC4 domain-containing protein.
    
 0.982
A0A1E3Q2J6
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.982
A0A1E3Q1P5
Uncharacterized protein.
    
 0.973
A0A1E3QC05
DNA helicase; Belongs to the MCM family.
   
 0.973
A0A1E3QEV7
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
   
   0.968
Your Current Organism:
Lipomyces starkeyi
NCBI taxonomy Id: 675824
Other names: L. starkeyi NRRL Y-11557, Lipomyces starkeyi NRRL Y-11557
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