STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein- mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck; Belongs to the WD repeat LIS1/nudF family. (451 aa)    
Predicted Functional Partners:
LIPSTDRAFT_929
Uncharacterized protein.
    
 0.994
A0A1E3QFG1
CS domain-containing protein.
    
 0.927
A0A1E3QFJ7
Uncharacterized protein.
   
 0.927
A0A1E3QDL1
Uncharacterized protein.
    
 0.893
A0A1E3PZB6
Dynactin domain-containing protein.
    
 0.891
A0A1E3Q1U0
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
    
 0.877
A0A1E3PV71
Uncharacterized protein.
   
 0.844
LIPSTDRAFT_637
Uncharacterized protein.
    
 0.840
A0A1E3Q0T2
Zinc_ribbon_15 domain-containing protein.
    
 0.774
A0A1E3PZI0
PH domain-containing protein.
    
 0.772
Your Current Organism:
Lipomyces starkeyi
NCBI taxonomy Id: 675824
Other names: L. starkeyi NRRL Y-11557, Lipomyces starkeyi NRRL Y-11557
Server load: low (16%) [HD]