STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1E3Q5G4Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (451 aa)    
Predicted Functional Partners:
LIPSTDRAFT_275
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.763
A0A1E3Q4W3
Pribosyltran domain-containing protein.
     
 0.750
A0A1E3QEK4
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
 
 
 
  0.747
A0A1E3Q3Q6
IU_nuc_hydro domain-containing protein.
    
 0.719
MEU1
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
    
 0.673
A0A1E3Q2S6
Uncharacterized protein; Belongs to the 5'-nucleotidase family.
     
 0.624
A0A1E3PZ96
Pribosyltran domain-containing protein.
     
 0.618
A0A1E3Q7U5
Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 
 0.611
A0A1E3Q2L6
Metallophos domain-containing protein.
     
 0.604
A0A1E3QFJ4
Uncharacterized protein.
   
 
  0.583
Your Current Organism:
Lipomyces starkeyi
NCBI taxonomy Id: 675824
Other names: L. starkeyi NRRL Y-11557, Lipomyces starkeyi NRRL Y-11557
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.