STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1E3Q9M8Protein kinase domain-containing protein. (462 aa)    
Predicted Functional Partners:
A0A1E3PXK4
DBF4-type domain-containing protein.
   
 0.999
A0A1E3QC05
DNA helicase; Belongs to the MCM family.
   
 0.996
A0A1E3QBQ6
DNA helicase; Belongs to the MCM family.
   
 0.994
A0A1E3PWY5
DNA helicase; Belongs to the MCM family.
   
 0.990
A0A1E3Q0E6
DNA helicase; Belongs to the MCM family.
   
 0.988
LIPSTDRAFT_310
DNA helicase; Belongs to the MCM family.
   
 0.988
A0A1E3Q2J6
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.987
A0A1E3QGN0
Serine/threonine-protein kinase RAD53; Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.
    
 
 0.986
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
    
 0.985
A0A1E3Q0R2
Zf-primase domain-containing protein.
   
 0.974
Your Current Organism:
Lipomyces starkeyi
NCBI taxonomy Id: 675824
Other names: L. starkeyi NRRL Y-11557, Lipomyces starkeyi NRRL Y-11557
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.