STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDE11299.1Lipoate-protein ligase A. (360 aa)    
Predicted Functional Partners:
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.983
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
 
 0.925
SDE18876.1
2-oxoglutarate dehydrogenase E1 component.
  
 0.923
lipB
Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
   
 0.903
SDE55899.1
2-oxoglutarate dehydrogenase E2 component.
 
 0.845
SDD18811.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 0.820
SDE08503.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 0.820
SDD18859.1
Pyruvate dehydrogenase E1 component beta subunit.
  
 
 0.814
SDE08529.1
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.814
SDD18896.1
Pyruvate dehydrogenase E1 component alpha subunit; Manually curated.
  
 
 0.778
Your Current Organism:
Auraticoccus monumenti
NCBI taxonomy Id: 675864
Other names: A. monumenti, Auraticoccus monumenti Alonso-Vega et al. 2011, CECT 7672, DSM 23257, LMG 25551, LMG:25551, Propionibacteriaceae bacterium MON 2.2, strain MON 2.2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.