STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEE27150.1Peptide methionine sulfoxide reductase. (229 aa)    
Predicted Functional Partners:
AEB28226.1
Peptide methionine sulfoxide reductase MsrB.
 
 0.985
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.783
AEE27149.1
Hypothetical protein.
       0.781
AEE26229.1
Hypothetical protein.
     
 0.625
trpC
Indole-3-glycerol phosphate synthase / Phosphoribosylanthranilate isomerase; Belongs to the TrpC family.
  
    0.577
AEE27151.1
Hypothetical protein.
       0.550
AEE27152.1
Hypothetical protein.
       0.550
msrA
Peptide methionine sulfoxide reductase MsrB / Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 
0.544
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.529
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
    0.501
Your Current Organism:
Francisella tularensis novicida
NCBI taxonomy Id: 676032
Other names: F. cf. tularensis subsp. novicida 3523, Francisella cf. novicida 3523, Francisella cf. tularensis subsp. novicida 3523, Francisella sp. 3523
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.