node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARD39729.1 | ARD40138.1 | B6E78_10350 | B6E78_12830 | Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protease modulator HflK; HflC and HflK could encode or regulate a protease. | 0.434 |
ARD39729.1 | ARD40139.1 | B6E78_10350 | B6E78_12835 | Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protease modulator HflC; HflC and HflK could regulate a protease. | 0.434 |
ARD39729.1 | hflB | B6E78_10350 | B6E78_13055 | Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.590 |
ARD39729.1 | nuoC | B6E78_10350 | B6E78_05385 | Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.991 |
ARD40138.1 | ARD39729.1 | B6E78_12830 | B6E78_10350 | Protease modulator HflK; HflC and HflK could encode or regulate a protease. | Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.434 |
ARD40138.1 | ARD40139.1 | B6E78_12830 | B6E78_12835 | Protease modulator HflK; HflC and HflK could encode or regulate a protease. | Protease modulator HflC; HflC and HflK could regulate a protease. | 0.988 |
ARD40138.1 | glpG | B6E78_12830 | B6E78_10045 | Protease modulator HflK; HflC and HflK could encode or regulate a protease. | Rhomboid family intramembrane serine protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.477 |
ARD40138.1 | hflB | B6E78_12830 | B6E78_13055 | Protease modulator HflK; HflC and HflK could encode or regulate a protease. | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.924 |
ARD40138.1 | hflX | B6E78_12830 | B6E78_12825 | Protease modulator HflK; HflC and HflK could encode or regulate a protease. | GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.908 |
ARD40138.1 | hfq | B6E78_12830 | B6E78_12820 | Protease modulator HflK; HflC and HflK could encode or regulate a protease. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.526 |
ARD40138.1 | miaA | B6E78_12830 | B6E78_12815 | Protease modulator HflK; HflC and HflK could encode or regulate a protease. | tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.630 |
ARD40138.1 | nuoC | B6E78_12830 | B6E78_05385 | Protease modulator HflK; HflC and HflK could encode or regulate a protease. | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.529 |
ARD40138.1 | yidC | B6E78_12830 | B6E78_11175 | Protease modulator HflK; HflC and HflK could encode or regulate a protease. | Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.599 |
ARD40139.1 | ARD39729.1 | B6E78_12835 | B6E78_10350 | Protease modulator HflC; HflC and HflK could regulate a protease. | Peptidase M16; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.434 |
ARD40139.1 | ARD40138.1 | B6E78_12835 | B6E78_12830 | Protease modulator HflC; HflC and HflK could regulate a protease. | Protease modulator HflK; HflC and HflK could encode or regulate a protease. | 0.988 |
ARD40139.1 | engB | B6E78_12835 | B6E78_10895 | Protease modulator HflC; HflC and HflK could regulate a protease. | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.495 |
ARD40139.1 | glpG | B6E78_12835 | B6E78_10045 | Protease modulator HflC; HflC and HflK could regulate a protease. | Rhomboid family intramembrane serine protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.477 |
ARD40139.1 | hflB | B6E78_12835 | B6E78_13055 | Protease modulator HflC; HflC and HflK could regulate a protease. | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.885 |
ARD40139.1 | hflX | B6E78_12835 | B6E78_12825 | Protease modulator HflC; HflC and HflK could regulate a protease. | GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.812 |
ARD40139.1 | hfq | B6E78_12835 | B6E78_12820 | Protease modulator HflC; HflC and HflK could regulate a protease. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.522 |