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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A1B0API11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1245 aa)    
Predicted Functional Partners:
A0A1B0BGG1
Receptor protein-tyrosine kinase.
    
 0.996
A0A1B0ASF9
Receptor protein-tyrosine kinase.
    
 0.985
A0A1B0B7F3
Uncharacterized protein.
    
 0.977
A0A1B0BT98
Uncharacterized protein.
    
 0.977
A0A1B0C6B4
Uncharacterized protein.
    
 0.977
A0A1B0BB98
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.973
A0A1B0B1I4
SH2 domain-containing protein.
   
 0.962
A0A1B0BSM0
Phosphatidylinositol 3-kinase catalytic subunit type 3.
     
 0.950
A0A1B0APW4
Uncharacterized protein.
    
 0.948
A0A1B0APW5
Uncharacterized protein.
    
 0.948
Your Current Organism:
Glossina palpalis
NCBI taxonomy Id: 67801
Other names: G. palpalis gambiensis, Glossina palpalis gambiensis
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