| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KMK51029.1 | KMK52271.1 | RO21_08610 | RO21_01395 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Outer membrane-specific lipoprotein transporter subunit LolE; Part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.597 |
| KMK51029.1 | lolA | RO21_08610 | RO21_02260 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.824 |
| KMK51029.1 | lolD | RO21_08610 | RO21_01400 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | 0.940 |
| KMK51029.1 | macB | RO21_08610 | RO21_04165 | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.983 |
| KMK51316.1 | lolD | RO21_06760 | RO21_01400 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | 0.603 |
| KMK51316.1 | macB | RO21_06760 | RO21_04165 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.999 |
| KMK51492.1 | KMK51510.1 | RO21_05915 | RO21_05765 | Peptide ABC transporter ATP-binding protein; Involved in resistance to antimibial peptides; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. | Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.773 |
| KMK51492.1 | lolD | RO21_05915 | RO21_01400 | Peptide ABC transporter ATP-binding protein; Involved in resistance to antimibial peptides; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. | ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | 0.681 |
| KMK51510.1 | KMK51492.1 | RO21_05765 | RO21_05915 | Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide ABC transporter ATP-binding protein; Involved in resistance to antimibial peptides; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily. | 0.773 |
| KMK51510.1 | lolD | RO21_05765 | RO21_01400 | Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | 0.748 |
| KMK51930.1 | lolD | RO21_03660 | RO21_01400 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | 0.603 |
| KMK51930.1 | macB | RO21_03660 | RO21_04165 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.999 |
| KMK52066.1 | lolD | RO21_02795 | RO21_01400 | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | 0.603 |
| KMK52066.1 | macB | RO21_02795 | RO21_04165 | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.999 |
| KMK52271.1 | KMK51029.1 | RO21_01395 | RO21_08610 | Outer membrane-specific lipoprotein transporter subunit LolE; Part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.597 |
| KMK52271.1 | eno | RO21_01395 | RO21_01405 | Outer membrane-specific lipoprotein transporter subunit LolE; Part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.513 |
| KMK52271.1 | lolA | RO21_01395 | RO21_02260 | Outer membrane-specific lipoprotein transporter subunit LolE; Part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.821 |
| KMK52271.1 | lolD | RO21_01395 | RO21_01400 | Outer membrane-specific lipoprotein transporter subunit LolE; Part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. | 0.984 |
| KMK52271.1 | macB | RO21_01395 | RO21_04165 | Outer membrane-specific lipoprotein transporter subunit LolE; Part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.983 |
| eno | KMK52271.1 | RO21_01405 | RO21_01395 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Outer membrane-specific lipoprotein transporter subunit LolE; Part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.513 |