| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KMK50891.1 | KMK51173.1 | RO21_09180 | RO21_07665 | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.792 |
| KMK50891.1 | guaA | RO21_09180 | RO21_10020 | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.459 |
| KMK50891.1 | queC | RO21_09180 | RO21_09175 | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.985 |
| KMK50891.1 | queF | RO21_09180 | RO21_03220 | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.854 |
| KMK51173.1 | KMK50891.1 | RO21_07665 | RO21_09180 | Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.792 |
| KMK51173.1 | KMK51178.1 | RO21_07665 | RO21_07670 | Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Ribonucleoside-triphosphate reductase; Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.978 |
| KMK51173.1 | guaA | RO21_07665 | RO21_10020 | Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.472 |
| KMK51173.1 | queC | RO21_07665 | RO21_09175 | Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.665 |
| KMK51173.1 | queF | RO21_07665 | RO21_03220 | Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.817 |
| KMK51178.1 | KMK51173.1 | RO21_07670 | RO21_07665 | Ribonucleoside-triphosphate reductase; Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.978 |
| guaA | KMK50891.1 | RO21_10020 | RO21_09180 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.459 |
| guaA | KMK51173.1 | RO21_10020 | RO21_07665 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.472 |
| guaA | queF | RO21_10020 | RO21_03220 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.683 |
| queC | KMK50891.1 | RO21_09175 | RO21_09180 | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
| queC | KMK51173.1 | RO21_09175 | RO21_07665 | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.665 |
| queC | queF | RO21_09175 | RO21_03220 | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.963 |
| queF | KMK50891.1 | RO21_03220 | RO21_09180 | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.854 |
| queF | KMK51173.1 | RO21_03220 | RO21_07665 | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.817 |
| queF | guaA | RO21_03220 | RO21_10020 | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.683 |
| queF | queC | RO21_03220 | RO21_09175 | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.963 |