close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpdA3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (275 aa)    
Predicted Functional Partners:
KMK51260.1
Aerobic respiration control protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.940
KMK51393.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.896
KMK51410.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the adenylyl cyclase class-1 family.
  
  
 0.811
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.763
KMK51534.1
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.754
KMK50692.1
Cyclic AMP receptor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.585
lysM
Peptidoglycan-binding protein LysM; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.570
KMK51632.1
Fimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.550
KMK51223.1
Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alkaline phosphatase family.
    
 0.539
KMK51740.1
Pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.534
Your Current Organism:
Muribacter muris
NCBI taxonomy Id: 67855
Other names: ATCC 49577, Ackerman 80-443D, Actinobacillus muris, CCUG 16938, CCUG 23134, CCUG 28285 B, CIP 103439, DSM 22206, M. muris, MCCM 00197, MCCM:00197, NCTC 12432, strain 80-443D, strain HIM 728-7/8, strain HIM 733-8
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.