STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pxpALamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (247 aa)    
Predicted Functional Partners:
KMK50849.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
KMK50850.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
KMK52101.1
Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
  0.855
KMK50852.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.742
KMK50847.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-glutamate cyclase family.
  
    0.702
KMK50848.1
DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.558
KMK50950.1
Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.526
KMK50732.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.526
KMK50854.1
Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.508
gltA
Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
   
    0.483
Your Current Organism:
Muribacter muris
NCBI taxonomy Id: 67855
Other names: ATCC 49577, Ackerman 80-443D, Actinobacillus muris, CCUG 16938, CCUG 23134, CCUG 28285 B, CIP 103439, DSM 22206, M. muris, MCCM 00197, MCCM:00197, NCTC 12432, strain 80-443D, strain HIM 728-7/8, strain HIM 733-8
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