STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menA1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (367 aa)    
Predicted Functional Partners:
EFA92062.1
Identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; uncharacterized domain 1.
 
  
 0.854
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
 
  
 0.847
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.817
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
   
 0.809
EFA91242.1
Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
    
 0.801
EFA91757.1
HD domain protein; Identified by match to protein family HMM PF01966.
  
    0.718
EFA92068.1
Hypothetical protein.
 
   
 0.715
EFA92063.1
Isochorismate synthase; Identified by match to protein family HMM PF00425.
 
   
 0.598
EFA91194.1
acyl-CoA thioester hydrolase, YbgC/YbaW family; Identified by match to protein family HMM PF03061.
    
 0.483
EFA92397.1
FAD dependent oxidoreductase; Identified by match to protein family HMM PF01266.
    
 0.462
Your Current Organism:
Prevotella buccalis
NCBI taxonomy Id: 679190
Other names: P. buccalis ATCC 35310, Prevotella buccalis ATCC 35310, Prevotella buccalis str. ATCC 35310, Prevotella buccalis strain ATCC 35310
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