Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
dprADNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. (379 aa)    
Predicted Functional Partners:
EFA91197.1
Mg chelatase-like protein; Identified by match to protein family HMM PF01078; match to protein family HMM PF07728; match to protein family HMM TIGR00368.
 
 
 0.840
EFA90845.1
Identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360.
 
  
 0.829
EFA91194.1
acyl-CoA thioester hydrolase, YbgC/YbaW family; Identified by match to protein family HMM PF03061.
  
    0.816
EFA93107.1
comF family protein.
 
 
 0.796
EFA91195.1
Hypothetical protein.
 
     0.667
EFA91192.1
TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.615
EFA90878.1
Identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621.
 
  
 0.554
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.476
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
 
   
 0.469
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
     0.430
Your Current Organism:
Prevotella buccalis
NCBI taxonomy Id: 679190
Other names: P. buccalis ATCC 35310, Prevotella buccalis ATCC 35310, Prevotella buccalis str. ATCC 35310, Prevotella buccalis strain ATCC 35310
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