STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepD-2Xaa-His dipeptidase; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893. (485 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.800
pepD
Xaa-His dipeptidase; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893.
  
  
 
0.789
EFA90963.1
Aminotransferase, class I/II; Identified by match to protein family HMM PF00155.
   
  0.788
EFA92258.1
Aminotransferase, class I/II; Identified by match to protein family HMM PF00155.
   
  0.788
cysK
Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.767
EFA91487.1
Aminotransferase, class I/II; Identified by match to protein family HMM PF00155.
    
  0.767
EFA92051.1
Hypothetical protein.
       0.695
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.547
EFA92538.1
Peptidase, M24 family; Identified by match to protein family HMM PF00557.
  
 
 0.481
EFA91490.1
Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Belongs to the peptidase M24B family.
  
 
 0.477
Your Current Organism:
Prevotella buccalis
NCBI taxonomy Id: 679190
Other names: P. buccalis ATCC 35310, Prevotella buccalis ATCC 35310, Prevotella buccalis str. ATCC 35310, Prevotella buccalis strain ATCC 35310
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.