Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
folBDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (126 aa)    
Predicted Functional Partners:
folP
Dihydropteroate synthase; Identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496.
 
 
 0.996
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498.
 
 
 0.992
folE
GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.
 
  
 0.928
EFA91843.1
Identified by match to protein family HMM PF00245; Belongs to the alkaline phosphatase family.
     
 0.900
EFA92336.1
Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase.
  
 
 0.885
EFA92406.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
       0.800
EFA92404.1
N-acetylmuramoyl-L-alanine amidase; Identified by match to protein family HMM PF01520.
       0.697
EFA92403.1
Identified by match to protein family HMM PF02470.
   
   0.685
EFA92407.1
Identified by match to protein family HMM PF00881; Belongs to the flavin oxidoreductase frp family.
     
 0.608
folC
Bifunctional protein FolC; Identified by match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.
  
  
 0.570
Your Current Organism:
Prevotella buccalis
NCBI taxonomy Id: 679190
Other names: P. buccalis ATCC 35310, Prevotella buccalis ATCC 35310, Prevotella buccalis str. ATCC 35310, Prevotella buccalis strain ATCC 35310
Server load: low (24%) [HD]