Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
lepBSignal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. (471 aa)    
Predicted Functional Partners:
EFA93117.1
Identified by match to protein family HMM PF08889.
 
     0.756
EFA93131.1
Outer membrane protein, OMP85 family; Identified by match to protein family HMM PF01103; match to protein family HMM PF07244.
  
  
 0.725
EFA93116.1
Peptidase S24-like protein; Identified by match to protein family HMM PF00717; Belongs to the peptidase S26 family.
       0.709
dapB
Dihydrodipicolinate reductase; Identified by match to protein family HMM PF01113; match to protein family HMM PF05173; match to protein family HMM TIGR00036; Belongs to the DapB family.
 
    0.701
EFA93074.1
Putative zinc ribbon domain protein; Identified by match to protein family HMM PF02591.
  
     0.682
EFA92800.1
Tetratricopeptide repeat protein; Identified by match to protein family HMM PF07719.
  
     0.666
EFA91875.1
Putative RIP metalloprotease RseP; Identified by match to protein family HMM PF02163.
 
  
 0.659
EFA93065.1
Hypothetical protein.
  
  
 0.645
yidC
Membrane protein insertase, YidC/Oxa1 family domain protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
  
 0.638
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.598
Your Current Organism:
Prevotella buccalis
NCBI taxonomy Id: 679190
Other names: P. buccalis ATCC 35310, Prevotella buccalis ATCC 35310, Prevotella buccalis str. ATCC 35310, Prevotella buccalis strain ATCC 35310
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