| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFC05336.1 | yeaZ | HMPREF9013_1361 | HMPREF9013_0002 | uracil-DNA glycosylase, family 4; Identified by match to protein family HMM PF03167. | Universal bacterial protein YeaZ; Identified by match to protein family HMM PF00814; match to protein family HMM TIGR03725. | 0.503 |
| EFC05811.1 | EFC05817.1 | HMPREF9013_0001 | HMPREF9013_0007 | Hydrolase, P-loop family; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | 0.550 |
| EFC05811.1 | asnS | HMPREF9013_0001 | HMPREF9013_0006 | Hydrolase, P-loop family; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | asparagine--tRNA ligase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | 0.675 |
| EFC05811.1 | rex | HMPREF9013_0001 | HMPREF9013_0005 | Hydrolase, P-loop family; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | CoA binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.679 |
| EFC05811.1 | rimI | HMPREF9013_0001 | HMPREF9013_0003 | Hydrolase, P-loop family; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. | 0.864 |
| EFC05811.1 | tsaD | HMPREF9013_0001 | HMPREF9013_0004 | Hydrolase, P-loop family; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.971 |
| EFC05811.1 | yeaZ | HMPREF9013_0001 | HMPREF9013_0002 | Hydrolase, P-loop family; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Universal bacterial protein YeaZ; Identified by match to protein family HMM PF00814; match to protein family HMM TIGR03725. | 0.997 |
| EFC05817.1 | EFC05811.1 | HMPREF9013_0007 | HMPREF9013_0001 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Hydrolase, P-loop family; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.550 |
| EFC05817.1 | asnS | HMPREF9013_0007 | HMPREF9013_0006 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | asparagine--tRNA ligase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | 0.808 |
| EFC05817.1 | pfp | HMPREF9013_0007 | HMPREF9013_0008 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.588 |
| EFC05817.1 | rex | HMPREF9013_0007 | HMPREF9013_0005 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | CoA binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.721 |
| EFC05817.1 | rimI | HMPREF9013_0007 | HMPREF9013_0003 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. | 0.534 |
| EFC05817.1 | tsaD | HMPREF9013_0007 | HMPREF9013_0004 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.568 |
| EFC05817.1 | yeaZ | HMPREF9013_0007 | HMPREF9013_0002 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Universal bacterial protein YeaZ; Identified by match to protein family HMM PF00814; match to protein family HMM TIGR03725. | 0.580 |
| asnS | EFC05811.1 | HMPREF9013_0006 | HMPREF9013_0001 | asparagine--tRNA ligase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | Hydrolase, P-loop family; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.675 |
| asnS | EFC05817.1 | HMPREF9013_0006 | HMPREF9013_0007 | asparagine--tRNA ligase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | 0.808 |
| asnS | pfp | HMPREF9013_0006 | HMPREF9013_0008 | asparagine--tRNA ligase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.482 |
| asnS | rex | HMPREF9013_0006 | HMPREF9013_0005 | asparagine--tRNA ligase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | CoA binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.816 |
| asnS | rimI | HMPREF9013_0006 | HMPREF9013_0003 | asparagine--tRNA ligase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. | 0.673 |
| asnS | tsaD | HMPREF9013_0006 | HMPREF9013_0004 | asparagine--tRNA ligase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00457. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.641 |