node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFC05888.1 | ddl | HMPREF9013_0083 | HMPREF9013_0162 | Hydrolase, alpha/beta domain protein; Identified by match to protein family HMM PF00561. | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.728 |
EFC05888.1 | murF | HMPREF9013_0083 | HMPREF9013_0084 | Hydrolase, alpha/beta domain protein; Identified by match to protein family HMM PF00561. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245. | 0.951 |
alr | ddl | HMPREF9013_0858 | HMPREF9013_0162 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.966 |
alr | mraY | HMPREF9013_0858 | HMPREF9013_0595 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.739 |
alr | murC | HMPREF9013_0858 | HMPREF9013_0241 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.835 |
alr | murD | HMPREF9013_0858 | HMPREF9013_0592 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Identified by match to protein family HMM PF08245; match to protein family HMM TIGR01087; Belongs to the MurCDEF family. | 0.767 |
alr | murE | HMPREF9013_0858 | HMPREF9013_0524 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.730 |
alr | murE-2 | HMPREF9013_0858 | HMPREF9013_0767 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.727 |
alr | murF | HMPREF9013_0858 | HMPREF9013_0084 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245. | 0.974 |
alr | murG | HMPREF9013_0858 | HMPREF9013_0420 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Putative undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.664 |
alr | pbpB | HMPREF9013_0858 | HMPREF9013_0596 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Penicillin-binding protein 2B; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | 0.701 |
ddl | EFC05888.1 | HMPREF9013_0162 | HMPREF9013_0083 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Hydrolase, alpha/beta domain protein; Identified by match to protein family HMM PF00561. | 0.728 |
ddl | alr | HMPREF9013_0162 | HMPREF9013_0858 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.966 |
ddl | mraY | HMPREF9013_0162 | HMPREF9013_0595 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.803 |
ddl | murC | HMPREF9013_0162 | HMPREF9013_0241 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.991 |
ddl | murD | HMPREF9013_0162 | HMPREF9013_0592 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Identified by match to protein family HMM PF08245; match to protein family HMM TIGR01087; Belongs to the MurCDEF family. | 0.924 |
ddl | murE | HMPREF9013_0162 | HMPREF9013_0524 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.739 |
ddl | murE-2 | HMPREF9013_0162 | HMPREF9013_0767 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.708 |
ddl | murF | HMPREF9013_0162 | HMPREF9013_0084 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245. | 0.994 |
ddl | murG | HMPREF9013_0162 | HMPREF9013_0420 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Putative undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.858 |