node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFC05304.1 | EFC05803.1 | HMPREF9013_0589 | HMPREF9013_0728 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Hypothetical protein; Identified by glimmer; putative. | 0.404 |
EFC05304.1 | EFC05806.1 | HMPREF9013_0589 | HMPREF9013_0731 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Identified by match to protein family HMM PF02541. | 0.819 |
EFC05304.1 | EFC05874.1 | HMPREF9013_0589 | HMPREF9013_0068 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DHHA2 domain protein; Identified by match to protein family HMM PF00571; match to protein family HMM PF02833. | 0.509 |
EFC05304.1 | EFC05964.1 | HMPREF9013_0589 | HMPREF9013_0166 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | CBS domain protein; Identified by match to protein family HMM PF00571; match to protein family HMM PF02833. | 0.509 |
EFC05304.1 | cgtA | HMPREF9013_0589 | HMPREF9013_0290 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.759 |
EFC05304.1 | polA | HMPREF9013_0589 | HMPREF9013_0713 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.677 |
EFC05803.1 | EFC05304.1 | HMPREF9013_0728 | HMPREF9013_0589 | Hypothetical protein; Identified by glimmer; putative. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.404 |
EFC05803.1 | EFC05806.1 | HMPREF9013_0728 | HMPREF9013_0731 | Hypothetical protein; Identified by glimmer; putative. | Identified by match to protein family HMM PF02541. | 0.596 |
EFC05803.1 | frr | HMPREF9013_0728 | HMPREF9013_0729 | Hypothetical protein; Identified by glimmer; putative. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.488 |
EFC05803.1 | pyrH | HMPREF9013_0728 | HMPREF9013_0730 | Hypothetical protein; Identified by glimmer; putative. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.502 |
EFC05806.1 | EFC05304.1 | HMPREF9013_0731 | HMPREF9013_0589 | Identified by match to protein family HMM PF02541. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.819 |
EFC05806.1 | EFC05803.1 | HMPREF9013_0731 | HMPREF9013_0728 | Identified by match to protein family HMM PF02541. | Hypothetical protein; Identified by glimmer; putative. | 0.596 |
EFC05806.1 | EFC05874.1 | HMPREF9013_0731 | HMPREF9013_0068 | Identified by match to protein family HMM PF02541. | DHHA2 domain protein; Identified by match to protein family HMM PF00571; match to protein family HMM PF02833. | 0.477 |
EFC05806.1 | EFC05964.1 | HMPREF9013_0731 | HMPREF9013_0166 | Identified by match to protein family HMM PF02541. | CBS domain protein; Identified by match to protein family HMM PF00571; match to protein family HMM PF02833. | 0.477 |
EFC05806.1 | cgtA | HMPREF9013_0731 | HMPREF9013_0290 | Identified by match to protein family HMM PF02541. | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.424 |
EFC05806.1 | frr | HMPREF9013_0731 | HMPREF9013_0729 | Identified by match to protein family HMM PF02541. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.554 |
EFC05806.1 | polA | HMPREF9013_0731 | HMPREF9013_0713 | Identified by match to protein family HMM PF02541. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.449 |
EFC05806.1 | pyrH | HMPREF9013_0731 | HMPREF9013_0730 | Identified by match to protein family HMM PF02541. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.554 |
EFC05874.1 | EFC05304.1 | HMPREF9013_0068 | HMPREF9013_0589 | DHHA2 domain protein; Identified by match to protein family HMM PF00571; match to protein family HMM PF02833. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.509 |
EFC05874.1 | EFC05806.1 | HMPREF9013_0068 | HMPREF9013_0731 | DHHA2 domain protein; Identified by match to protein family HMM PF00571; match to protein family HMM PF02833. | Identified by match to protein family HMM PF02541. | 0.477 |