STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFC06043.1Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440. (169 aa)    
Predicted Functional Partners:
EFC06044.1
Hypothetical protein.
       0.527
EFC06045.1
Hypothetical protein.
       0.527
EFC06046.1
Hypothetical protein; Identified by glimmer; putative.
       0.527
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.483
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.466
EFC06042.1
Cna protein B-type domain protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF05738.
       0.440
dprA
DNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732.
  
    0.410
xerC
Phage integrase SAM-like domain protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
  
  
 0.405
Your Current Organism:
Bulleidia extructa
NCBI taxonomy Id: 679192
Other names: B. extructa W1219, Bulleidia extructa W1219, Bulleidia extructa str. W1219, Bulleidia extructa strain W1219
Server load: low (30%) [HD]