node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFC06044.1 | dprA | HMPREF9013_0736 | HMPREF9013_0742 | Hypothetical protein. | DNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | 0.565 |
EFC06044.1 | lepB | HMPREF9013_0736 | HMPREF9013_0745 | Hypothetical protein. | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | 0.474 |
EFC06044.1 | rnhB | HMPREF9013_0736 | HMPREF9013_0743 | Hypothetical protein. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.474 |
EFC06044.1 | topA | HMPREF9013_0736 | HMPREF9013_0741 | Hypothetical protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.557 |
EFC06044.1 | trmFO | HMPREF9013_0736 | HMPREF9013_0740 | Hypothetical protein. | tRNA:m(5)U-54 methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.557 |
EFC06044.1 | xerC | HMPREF9013_0736 | HMPREF9013_0739 | Hypothetical protein. | Phage integrase SAM-like domain protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.557 |
EFC06044.1 | ylqF | HMPREF9013_0736 | HMPREF9013_0744 | Hypothetical protein. | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.474 |
dprA | EFC06044.1 | HMPREF9013_0742 | HMPREF9013_0736 | DNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | Hypothetical protein. | 0.565 |
dprA | lepB | HMPREF9013_0742 | HMPREF9013_0745 | DNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | 0.730 |
dprA | rnhB | HMPREF9013_0742 | HMPREF9013_0743 | DNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.734 |
dprA | rplS | HMPREF9013_0742 | HMPREF9013_0746 | DNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.564 |
dprA | topA | HMPREF9013_0742 | HMPREF9013_0741 | DNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.932 |
dprA | trmFO | HMPREF9013_0742 | HMPREF9013_0740 | DNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | tRNA:m(5)U-54 methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.804 |
dprA | xerC | HMPREF9013_0742 | HMPREF9013_0739 | DNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | Phage integrase SAM-like domain protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.838 |
dprA | ylqF | HMPREF9013_0742 | HMPREF9013_0744 | DNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.732 |
lepA | lepB | HMPREF9013_0505 | HMPREF9013_0745 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | 0.618 |
lepA | rplS | HMPREF9013_0505 | HMPREF9013_0746 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.953 |
lepA | topA | HMPREF9013_0505 | HMPREF9013_0741 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.525 |
lepB | EFC06044.1 | HMPREF9013_0745 | HMPREF9013_0736 | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | Hypothetical protein. | 0.474 |
lepB | dprA | HMPREF9013_0745 | HMPREF9013_0742 | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | DNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. | 0.730 |