STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (213 aa)    
Predicted Functional Partners:
xth
Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633.
 
 0.999
rnfE
Electron transport complex, RnfABCDGE type, E subunit; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF02508; Belongs to the NqrDE/RnfAE family.
 
  
 0.947
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
  
 0.871
EFC06085.1
DnaD domain protein; Identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446.
  
  
 0.817
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.795
EFC05920.1
Putative A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
 
 
0.776
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
     
 0.776
EFC06086.1
Identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090.
  
    0.774
EFC06088.1
Putative RNA-binding protein, YhbY family; Identified by match to protein family HMM PF01985.
       0.767
EFC06087.1
Hydrolase, HD family; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR00488.
       0.766
Your Current Organism:
Bulleidia extructa
NCBI taxonomy Id: 679192
Other names: B. extructa W1219, Bulleidia extructa W1219, Bulleidia extructa str. W1219, Bulleidia extructa strain W1219
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