node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFC05355.1 | aroB | HMPREF9013_1380 | HMPREF9013_0800 | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.588 |
EFC05355.1 | aroC | HMPREF9013_1380 | HMPREF9013_0799 | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.472 |
EFC05355.1 | aroK | HMPREF9013_1380 | HMPREF9013_0798 | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.588 |
EFC05355.1 | aroQ | HMPREF9013_1380 | HMPREF9013_0795 | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | Dehydroquinase class II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.502 |
EFC05641.1 | EFC06067.1 | HMPREF9013_0246 | HMPREF9013_0759 | Identified by match to protein family HMM PF01041; Belongs to the DegT/DnrJ/EryC1 family. | Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. | 0.637 |
EFC05641.1 | aroQ | HMPREF9013_0246 | HMPREF9013_0795 | Identified by match to protein family HMM PF01041; Belongs to the DegT/DnrJ/EryC1 family. | Dehydroquinase class II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.555 |
EFC05641.1 | rimI | HMPREF9013_0246 | HMPREF9013_0003 | Identified by match to protein family HMM PF01041; Belongs to the DegT/DnrJ/EryC1 family. | Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. | 0.637 |
EFC06067.1 | EFC05641.1 | HMPREF9013_0759 | HMPREF9013_0246 | Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. | Identified by match to protein family HMM PF01041; Belongs to the DegT/DnrJ/EryC1 family. | 0.637 |
EFC06067.1 | aroB | HMPREF9013_0759 | HMPREF9013_0800 | Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.509 |
EFC06067.1 | aroQ | HMPREF9013_0759 | HMPREF9013_0795 | Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. | Dehydroquinase class II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.510 |
aroA | aroB | HMPREF9013_0796 | HMPREF9013_0800 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.999 |
aroA | aroC | HMPREF9013_0796 | HMPREF9013_0799 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.999 |
aroA | aroF | HMPREF9013_0796 | HMPREF9013_0797 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-deoxy-7-phosphoheptulonate synthase; Identified by match to protein family HMM PF00793; match to protein family HMM TIGR01361. | 0.890 |
aroA | aroK | HMPREF9013_0796 | HMPREF9013_0798 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.997 |
aroA | aroQ | HMPREF9013_0796 | HMPREF9013_0795 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Dehydroquinase class II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.937 |
aroB | EFC05355.1 | HMPREF9013_0800 | HMPREF9013_1380 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | 0.588 |
aroB | EFC06067.1 | HMPREF9013_0800 | HMPREF9013_0759 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. | 0.509 |
aroB | aroA | HMPREF9013_0800 | HMPREF9013_0796 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.999 |
aroB | aroC | HMPREF9013_0800 | HMPREF9013_0799 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.996 |
aroB | aroF | HMPREF9013_0800 | HMPREF9013_0797 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 3-deoxy-7-phosphoheptulonate synthase; Identified by match to protein family HMM PF00793; match to protein family HMM TIGR01361. | 0.997 |