STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFC05481.1Type I restriction modification DNA specificity domain protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01420. (174 aa)    
Predicted Functional Partners:
EFC05321.1
Type I restriction modification DNA specificity domain protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF01420.
 
 
 0.986
EFC05322.1
Putative type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384.
 
 
 0.969
EFC05506.1
Helicase C-terminal domain protein; Identified by match to protein family HMM PF00271; match to protein family HMM PF02384.
  
 
 0.872
EFC05482.1
Site-specific recombinase, phage integrase family; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family.
     
 0.751
atpF
ATP synthase B/B' CF(0); Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
   
 
 0.647
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.642
hsdR
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
  
  
 0.637
EFC05632.1
Hypothetical protein.
  
    0.528
EFC05507.1
Divergent AAA domain protein; Identified by match to protein family HMM PF04326.
  
    0.467
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
   0.423
Your Current Organism:
Bulleidia extructa
NCBI taxonomy Id: 679192
Other names: B. extructa W1219, Bulleidia extructa W1219, Bulleidia extructa str. W1219, Bulleidia extructa strain W1219
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