node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHI54825.1 | EHI55830.1 | HMPREF9333_02026 | HMPREF9333_00873 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | Hypothetical protein. | 0.871 |
EHI54825.1 | EHI56721.1 | HMPREF9333_02026 | HMPREF9333_00168 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | Hypothetical protein. | 0.889 |
EHI54825.1 | mutL | HMPREF9333_02026 | HMPREF9333_00760 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | Hypothetical protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.988 |
EHI54825.1 | polA | HMPREF9333_02026 | HMPREF9333_00580 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
EHI54825.1 | recA | HMPREF9333_02026 | HMPREF9333_00322 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | Hypothetical protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.912 |
EHI54825.1 | rpoB | HMPREF9333_02026 | HMPREF9333_01109 | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.603 |
EHI55830.1 | EHI54825.1 | HMPREF9333_00873 | HMPREF9333_02026 | Hypothetical protein. | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | 0.871 |
EHI55830.1 | EHI56721.1 | HMPREF9333_00873 | HMPREF9333_00168 | Hypothetical protein. | Hypothetical protein. | 0.910 |
EHI55830.1 | mutL | HMPREF9333_00873 | HMPREF9333_00760 | Hypothetical protein. | Hypothetical protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.798 |
EHI55830.1 | polA | HMPREF9333_00873 | HMPREF9333_00580 | Hypothetical protein. | Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.781 |
EHI55830.1 | radA | HMPREF9333_00873 | HMPREF9333_02145 | Hypothetical protein. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.511 |
EHI55830.1 | recA | HMPREF9333_00873 | HMPREF9333_00322 | Hypothetical protein. | Hypothetical protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.860 |
EHI55830.1 | rpoB | HMPREF9333_00873 | HMPREF9333_01109 | Hypothetical protein. | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.751 |
EHI56058.1 | lexA | HMPREF9333_00840 | HMPREF9333_00508 | Hypothetical protein; Belongs to the CinA family. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.568 |
EHI56058.1 | mutL | HMPREF9333_00840 | HMPREF9333_00760 | Hypothetical protein; Belongs to the CinA family. | Hypothetical protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.561 |
EHI56058.1 | polA | HMPREF9333_00840 | HMPREF9333_00580 | Hypothetical protein; Belongs to the CinA family. | Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.720 |
EHI56058.1 | recA | HMPREF9333_00840 | HMPREF9333_00322 | Hypothetical protein; Belongs to the CinA family. | Hypothetical protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.907 |
EHI56058.1 | recX | HMPREF9333_00840 | HMPREF9333_00321 | Hypothetical protein; Belongs to the CinA family. | Hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.604 |
EHI56721.1 | EHI54825.1 | HMPREF9333_00168 | HMPREF9333_02026 | Hypothetical protein. | DNA polymerase III; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...] | 0.889 |
EHI56721.1 | EHI55830.1 | HMPREF9333_00168 | HMPREF9333_00873 | Hypothetical protein. | Hypothetical protein. | 0.910 |