STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiAHypothetical protein; Involved in cell division and chromosome segregation. (318 aa)    
Predicted Functional Partners:
EHI56108.1
Hypothetical protein; Displays ATPase and GTPase activities.
 
  
 0.909
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
     
 0.847
EHI56715.1
Hypothetical protein; Belongs to the UPF0297 family.
  
     0.733
EHI55023.1
Hypothetical protein.
  
     0.684
EHI56110.1
Hypothetical protein.
  
  
 0.683
EHI56538.1
Hypothetical protein.
  
     0.667
hprK
HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...]
       0.654
EHI56198.1
Hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
  
 0.635
codY
Hypothetical protein; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
  
     0.572
polC
Hypothetical protein; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
     0.570
Your Current Organism:
Johnsonella ignava
NCBI taxonomy Id: 679200
Other names: J. ignava ATCC 51276, Johnsonella ignava ATCC 51276, Johnsonella ignava str. ATCC 51276, Johnsonella ignava strain ATCC 51276
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.