node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHI54819.1 | EHI55438.1 | HMPREF9333_02020 | HMPREF9333_01574 | Hypothetical protein. | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | 0.975 |
EHI54819.1 | EHI55885.1 | HMPREF9333_02020 | HMPREF9333_00928 | Hypothetical protein. | Preprotein translocase subunit. | 0.929 |
EHI54819.1 | EHI55952.1 | HMPREF9333_02020 | HMPREF9333_00995 | Hypothetical protein. | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.985 |
EHI54819.1 | ffh | HMPREF9333_02020 | HMPREF9333_00729 | Hypothetical protein. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.936 |
EHI54819.1 | ftsY | HMPREF9333_02020 | HMPREF9333_00515 | Hypothetical protein. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.917 |
EHI54819.1 | secA | HMPREF9333_02020 | HMPREF9333_01421 | Hypothetical protein. | Translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.942 |
EHI54819.1 | secF | HMPREF9333_02020 | HMPREF9333_00930 | Hypothetical protein. | Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.998 |
EHI54819.1 | secY | HMPREF9333_02020 | HMPREF9333_00256 | Hypothetical protein. | Preprotein translocase; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.991 |
EHI54946.1 | EHI55885.1 | HMPREF9333_01793 | HMPREF9333_00928 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Preprotein translocase subunit. | 0.606 |
EHI54946.1 | secF | HMPREF9333_01793 | HMPREF9333_00930 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.689 |
EHI55438.1 | EHI54819.1 | HMPREF9333_01574 | HMPREF9333_02020 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | Hypothetical protein. | 0.975 |
EHI55438.1 | EHI55885.1 | HMPREF9333_01574 | HMPREF9333_00928 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase subunit. | 0.865 |
EHI55438.1 | EHI55952.1 | HMPREF9333_01574 | HMPREF9333_00995 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.993 |
EHI55438.1 | ffh | HMPREF9333_01574 | HMPREF9333_00729 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.955 |
EHI55438.1 | ftsY | HMPREF9333_01574 | HMPREF9333_00515 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.952 |
EHI55438.1 | secA | HMPREF9333_01574 | HMPREF9333_01421 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | Translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.975 |
EHI55438.1 | secF | HMPREF9333_01574 | HMPREF9333_00930 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.995 |
EHI55438.1 | secY | HMPREF9333_01574 | HMPREF9333_00256 | Preprotein translocase; Belongs to the SecE/SEC61-gamma family. | Preprotein translocase; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.992 |
EHI55885.1 | EHI54819.1 | HMPREF9333_00928 | HMPREF9333_02020 | Preprotein translocase subunit. | Hypothetical protein. | 0.929 |
EHI55885.1 | EHI54946.1 | HMPREF9333_00928 | HMPREF9333_01793 | Preprotein translocase subunit. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.606 |