STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (294 aa)    
Predicted Functional Partners:
thrC
Threonine synthase; evidence=ISS; db_xref=cjejuni:Cj0812; date=20070321; method=automatic:reciprocal fasta.
 
 0.999
hom
Homoserine dehydrogenase; evidence=ISS; db_xref=cjejuni:Cj0149c; date=20070321; method=automatic:reciprocal fasta.
 
 0.992
purM
Phosphoribosylformylglycinamidine cyclo-ligase; evidence=ISS; db_xref=cjejuni:Cj1529c; date=20070321; method=automatic:reciprocal fasta.
 
    
 0.906
HMU01720
Putative septum site-determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
 
     0.833
sdaA
L-serine deaminase 1; evidence=ISS; db_xref=smarcescens:SMA2084; date=20070321; method=automatic:reciprocal fasta; Belongs to the iron-sulfur dependent L-serine dehydratase family.
   
 
 0.826
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.825
rbfA
Putative ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
 
     0.814
HMU01710
Putative periplasmic protein; evidence=IEA; db_xref=cjejuni:Cj0131; date=20070321; method=automatic:reciprocal fasta.
       0.803
lpxC
UDP-3-O-[3-hydroxymyristoyl] n-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
       0.803
HMU01740
Putative hypothetical protein.
       0.803
Your Current Organism:
Helicobacter mustelae
NCBI taxonomy Id: 679897
Other names: H. mustelae 12198, Helicobacter mustelae 12198, Helicobacter mustelae str. 12198, Helicobacter mustelae strain 12198
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.