node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HMU03240 | HMU03250 | HMU03240 | HMU03250 | Putative outer membrane protein; evidence=ISS. | Putative Dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.813 |
HMU03240 | HMU03270 | HMU03240 | HMU03270 | Putative outer membrane protein; evidence=ISS. | Putative poly(A) polymerase; evidence=ISS; db_xref=cdifficile:CD2466; date=20070321; method=automatic:reciprocal fasta; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.584 |
HMU03240 | queC | HMU03240 | HMU03260 | Putative outer membrane protein; evidence=ISS. | Putative queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.812 |
HMU03250 | HMU03240 | HMU03250 | HMU03240 | Putative Dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Putative outer membrane protein; evidence=ISS. | 0.813 |
HMU03250 | HMU03270 | HMU03250 | HMU03270 | Putative Dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Putative poly(A) polymerase; evidence=ISS; db_xref=cdifficile:CD2466; date=20070321; method=automatic:reciprocal fasta; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.712 |
HMU03250 | queC | HMU03250 | HMU03260 | Putative Dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Putative queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.814 |
HMU03270 | HMU03240 | HMU03270 | HMU03240 | Putative poly(A) polymerase; evidence=ISS; db_xref=cdifficile:CD2466; date=20070321; method=automatic:reciprocal fasta; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Putative outer membrane protein; evidence=ISS. | 0.584 |
HMU03270 | HMU03250 | HMU03270 | HMU03250 | Putative poly(A) polymerase; evidence=ISS; db_xref=cdifficile:CD2466; date=20070321; method=automatic:reciprocal fasta; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Putative Dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.712 |
HMU03270 | queC | HMU03270 | HMU03260 | Putative poly(A) polymerase; evidence=ISS; db_xref=cdifficile:CD2466; date=20070321; method=automatic:reciprocal fasta; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | Putative queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.589 |
HMU08210 | queC | HMU08210 | HMU03260 | Putative 6-pyruvoyl tetrahydrobiopterin synthase; evidence=ISS; db_xref=bcenocepacia:CAM2523; date=20070321; method=automatic:reciprocal fasta. | Putative queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.924 |
HMU08210 | queE | HMU08210 | HMU08200 | Putative 6-pyruvoyl tetrahydrobiopterin synthase; evidence=ISS; db_xref=bcenocepacia:CAM2523; date=20070321; method=automatic:reciprocal fasta. | Putative hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
HMU08210 | queF | HMU08210 | HMU03980 | Putative 6-pyruvoyl tetrahydrobiopterin synthase; evidence=ISS; db_xref=bcenocepacia:CAM2523; date=20070321; method=automatic:reciprocal fasta. | Putatuve NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.814 |
queA | queC | HMU01120 | HMU03260 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Putative queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.411 |
queC | HMU03240 | HMU03260 | HMU03240 | Putative queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative outer membrane protein; evidence=ISS. | 0.812 |
queC | HMU03250 | HMU03260 | HMU03250 | Putative queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative Dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.814 |
queC | HMU03270 | HMU03260 | HMU03270 | Putative queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative poly(A) polymerase; evidence=ISS; db_xref=cdifficile:CD2466; date=20070321; method=automatic:reciprocal fasta; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.589 |
queC | HMU08210 | HMU03260 | HMU08210 | Putative queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative 6-pyruvoyl tetrahydrobiopterin synthase; evidence=ISS; db_xref=bcenocepacia:CAM2523; date=20070321; method=automatic:reciprocal fasta. | 0.924 |
queC | queA | HMU03260 | HMU01120 | Putative queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.411 |
queC | queE | HMU03260 | HMU08200 | Putative queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putative hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.981 |
queC | queF | HMU03260 | HMU03980 | Putative queuosine biosynthesis protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Putatuve NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.985 |