| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ahpC | fdxA | HMU03320 | HMU03340 | Alkyl hydroperoxide reductase; evidence=ISS; db_xref=cjejuni:Cj0334; date=20070321; method=automatic:reciprocal fasta. | Ferredoxin; evidence=ISS; db_xref=cjejuni:Cj0333c; date=20070321; method=automatic:reciprocal fasta. | 0.412 |
| ahpC | guaA | HMU03320 | HMU12170 | Alkyl hydroperoxide reductase; evidence=ISS; db_xref=cjejuni:Cj0334; date=20070321; method=automatic:reciprocal fasta. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.415 |
| ahpC | metK | HMU03320 | HMU03330 | Alkyl hydroperoxide reductase; evidence=ISS; db_xref=cjejuni:Cj0334; date=20070321; method=automatic:reciprocal fasta. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.659 |
| fcl | metK | HMU00900 | HMU03330 | Putative GDP-L-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.590 |
| fdxA | ahpC | HMU03340 | HMU03320 | Ferredoxin; evidence=ISS; db_xref=cjejuni:Cj0333c; date=20070321; method=automatic:reciprocal fasta. | Alkyl hydroperoxide reductase; evidence=ISS; db_xref=cjejuni:Cj0334; date=20070321; method=automatic:reciprocal fasta. | 0.412 |
| fdxA | metK | HMU03340 | HMU03330 | Ferredoxin; evidence=ISS; db_xref=cjejuni:Cj0333c; date=20070321; method=automatic:reciprocal fasta. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.538 |
| glyA | guaA | HMU11200 | HMU12170 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.539 |
| glyA | metK | HMU11200 | HMU03330 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.712 |
| glyA | pheT | HMU11200 | HMU00550 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | phenylalanyl-tRNA synthetase beta chain; evidence=ISS; db_xref=cjejuni:Cj0896c; date=20070321; method=automatic:reciprocal fasta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.479 |
| glyA | purF | HMU11200 | HMU09220 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.811 |
| guaA | ahpC | HMU12170 | HMU03320 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Alkyl hydroperoxide reductase; evidence=ISS; db_xref=cjejuni:Cj0334; date=20070321; method=automatic:reciprocal fasta. | 0.415 |
| guaA | glyA | HMU12170 | HMU11200 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.539 |
| guaA | metK | HMU12170 | HMU03330 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.689 |
| guaA | pheT | HMU12170 | HMU00550 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase beta chain; evidence=ISS; db_xref=cjejuni:Cj0896c; date=20070321; method=automatic:reciprocal fasta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.933 |
| guaA | purF | HMU12170 | HMU09220 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.725 |
| metK | ahpC | HMU03330 | HMU03320 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Alkyl hydroperoxide reductase; evidence=ISS; db_xref=cjejuni:Cj0334; date=20070321; method=automatic:reciprocal fasta. | 0.659 |
| metK | fcl | HMU03330 | HMU00900 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Putative GDP-L-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. | 0.590 |
| metK | fdxA | HMU03330 | HMU03340 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Ferredoxin; evidence=ISS; db_xref=cjejuni:Cj0333c; date=20070321; method=automatic:reciprocal fasta. | 0.538 |
| metK | glyA | HMU03330 | HMU11200 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.712 |
| metK | guaA | HMU03330 | HMU12170 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.689 |