STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hupBDNA-binding protein HU homolog; evidence=ISS; db_xref=cjejuni:Cj0913c; date=20070321; method=automatic:reciprocal fasta; Belongs to the bacterial histone-like protein family. (93 aa)    
Predicted Functional Partners:
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.667
rpmF
50S ribosomal protein L32; evidence=ISS; db_xref=cjejuni:Cj0330c; date=20070321; method=automatic:reciprocal fasta; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.661
dnaA
Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.639
rpsO
30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
  
 0.561
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
    0.527
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
    0.514
pheA
Chorismate mutaseprephenate dehydratase; evidence=ISS; db_xref=cjejuni:Cj0316; date=20070321; method=automatic:reciprocal fasta.
     
 0.508
gapA
Glyceraldehyde 3-phosphate dehydrogenase; evidence=ISS; db_xref=cjejuni:Cj1403c; date=20070321; method=automatic:reciprocal fasta; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.501
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.495
trpF
N-(5'-phosphoribosyl)anthranilate isomerase; evidence=ISS; db_xref=ecarotovora_atroseptica:ECA2299; date=20070321; method=automatic:top fasta hit; Belongs to the TrpF family.
     
 0.480
Your Current Organism:
Helicobacter mustelae
NCBI taxonomy Id: 679897
Other names: H. mustelae 12198, Helicobacter mustelae 12198, Helicobacter mustelae str. 12198, Helicobacter mustelae strain 12198
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.