Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hupBDNA-binding protein HU homolog; evidence=ISS; db_xref=cjejuni:Cj0913c; date=20070321; method=automatic:reciprocal fasta; Belongs to the bacterial histone-like protein family. (93 aa)    
Predicted Functional Partners:
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 
 0.790
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
   0.742
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.702
dnaA
Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.625
rpmF
50S ribosomal protein L32; evidence=ISS; db_xref=cjejuni:Cj0330c; date=20070321; method=automatic:reciprocal fasta; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.593
rpsO
30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
  
 0.560
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
    0.515
pheA
Chorismate mutaseprephenate dehydratase; evidence=ISS; db_xref=cjejuni:Cj0316; date=20070321; method=automatic:reciprocal fasta.
     
 0.506
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.502
kefB
Putative glutathione-regulated potassium-efflux system protein; evidence=ISS; db_xref=cjejuni:Cj1231; date=20070321; method=automatic:reciprocal fasta; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
    
 
 0.502
Your Current Organism:
Helicobacter mustelae
NCBI taxonomy Id: 679897
Other names: H. mustelae 12198, Helicobacter mustelae 12198, Helicobacter mustelae str. 12198, Helicobacter mustelae strain 12198
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