STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cznAPutative Cadmium-zinc-nickel resistance protein, cznA; 16790756; ; evidence=ISS; db_xref=bcenocepacia:CAM0713; date=20070321; method=automatic:reciprocal fasta; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1019 aa)    
Predicted Functional Partners:
cznB
Putative Cadmium-zinc-nickel resistance protein, CznB; 16790756; ; evidence=ISS.
 
 
 0.980
cznC
Putative Cadmium-zinc-nickel outer membrane efflux protein, CznC; 16790756; ; evidence=ISS.
  
  
 0.933
crdC
Putative copper resistance determinant, CrdC; 12426358; ; evidence=ISS; db_xref=yenterocolitica:YE3629; date=20070321; method=automatic:top fasta hit.
 
 
 0.829
HMU07660
Putative hypothetical protein; evidence=ISS.
       0.814
crdB
Putative copper resistance determinant, CrdB; 12426358; ; evidence=ISS.
  
  
 0.749
HMU07580
Putative HlyD family secretion protein; evidence=ISS; db_xref=bcenocepacia:CAL1811; date=20070321; method=automatic:top fasta hit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.694
crdA
Putative copper resistance determinant, crdA; 12426358; ; evidence=ISS.
     
 0.628
rlmN
Putative radical-SAM-proteins; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
      
 0.618
trpA
Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
      
 0.618
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
      
 0.618
Your Current Organism:
Helicobacter mustelae
NCBI taxonomy Id: 679897
Other names: H. mustelae 12198, Helicobacter mustelae 12198, Helicobacter mustelae str. 12198, Helicobacter mustelae strain 12198
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.