Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dapDPossible 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (390 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase, DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
  
 
 0.943
argD
Succinylornithine transaminase, ArgD; evidence=ISS; db_xref=cdifficile:CD2031; date=20070321; method=automatic:reciprocal fasta; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
 0.915
HMU07750
Putative Sel1 repeat domain protein; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives.
   
   0.819
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
  
 0.765
hspR
Putative heat shock transcriptional regulator; evidence=ISS; db_xref=cjejuni:Cj1230; date=20070321; method=automatic:reciprocal fasta.
  
   
 0.670
FrpB2
Iron-regulated outer membrane protein FrpB2; evidence=ISS; db_xref=nmeningitidis_serogroupC_strainFAM18:NMC1963; date=20070321; method=automatic:top fasta hit.
  
   
 0.666
CeuE
Periplasmic iron-binding protein Iron(III) ABC transporter CeuE; evidence=ISS.
   
  
 0.621
groES
10 kD chaperonin (cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
   
  
 0.621
FecD
Putative iron compound ABC transporter, permease FecD; evidence=ISS; db_xref=pmirabilis:PMI2676; date=20070321; method=automatic:reciprocal fasta; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
      
 0.618
FecE
ABC transporter ATP-binding protein FecE; evidence=ISS; db_xref=ecarotovora_atroseptica:ECA3094; date=20070321; method=automatic:reciprocal fasta.
      
 0.618
Your Current Organism:
Helicobacter mustelae
NCBI taxonomy Id: 679897
Other names: H. mustelae 12198, Helicobacter mustelae 12198, Helicobacter mustelae str. 12198, Helicobacter mustelae strain 12198
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.